The Biomaterials and Regenerative Engineering lab, made up of around 20 members, including eight permanent lecturers-researchers at UPM and research assistants, as well as around ten undergraduate and graduate students, addresses biophysical-related questions in the fields of biomaterials, tissue engineering, biomechanics and mechanobiology. Our goal is to contribute to the understanding of the interplay between mechanical properties, internal structure, biological activity of cells and tissues and cells, and their interaction with biomaterials. We focus on the design and development of advanced smart biomaterials based on silk fibroins to optimize tissue and organ repair, in vitro on cellular models and in vivo on small animals. We also develop innovative biofunctionalization techniques for enhancing biocompatibility.
The team’s research activities are organized around five topics: (1) Bioinspired silk-based smart biomaterials for tissue engineering. (2) Biomechanics of soft tissues and development of soft biomaterials (collagen-based materials: esophagus, blood vessels…). (3) Functionalization of biomaterials to enhance cell/tissue signaling and biocompatibility. (4) Mechanobiology: development of methods to study mechanical aspects of cells and tissues.
